I have a long-standing research interest in two main areas: a) the cell biology of normal epithelial tissues and immune cells and b) understanding how the process of cancer development influences cellular proliferation, differentiation and response to death signals. With expertise in cancer and immunology, as well as a deep understanding of the biology of normal epithelial tissues, my work has led to projects with commercial and patient impact in the areas of novel therapeutics and medical devices.
 
My specific research interests can be summarised as follows:
• Studying the signalling cues that regulate cell survival versus death using appropriate epithelial cell models to understand normal tissue physiology and chronic disease
• Understanding the cellular responses to death (apoptosis) signals triggered by members of the TNF Receptor protein family as well as other types of cell death (such as necrosis, autophagy, ferroptosis)
• Exploring the cell signalling mechanisms that underpin: a) chemotherapy-induced hair loss (alopecia), b) chemotherapy drug-mediated neuropathic pain, and c) inadequate and/or defective wound healing
• Designing novel therapeutic strategies to develop improved tumour-specific anticancer therapeutic interventions
• Utilising our basic cell biology discoveries and knowledge to improve existing and/or to design novel medical devices that improve quality of life and/or aid patient health recovery. 

Currently, I have a major industrial research collaboration on chemotherapy-induced alopecia (CIA) and chemotherapy-induced peripheral neuropathy (CIPN) research with Paxman Ltd (https://paxmanscalpcooling.com/), and I am the Chief Scientific Officer & Co-Founder of the skin regeneration-focused company VeritaCell (https://veritacell.com/).

Paxman Ltd (https://paxmanscalpcooling.com/)
Project Youth Cancer (https://projectyouthcancer.org/)