Topics relating to Cell Biology, Cancer Biology and Immunology, and Pathology of Disease.

Postgraduate supervision

Areas of research supervision include (but are not limited to):
• Understanding the mechanisms of cell death (apoptosis) triggered by members of the TNF Receptor protein family for the design of novel cancer-specific, targeted therapeutics
• Studying the molecular mechanisms of novel types of cell death such as regulated necrosis, autophagy, and ferroptosis and their role in human pathophysiology as well as their potential as novel therapeutic targets
• Investigations of the mechanisms of chemotherapy drug-mediated hair loss (alopecia) using physiologically-relevant in vitro models and design of novel scalp cooling-based approaches to prevent hair loss in cancer patients
• Understanding the cell signalling pathways that underpin chemotherapy-induced peripheral neuropathy (CIPN) and designing novel cooling-based methods to combat chronic CIPN
• Use of physiologically-relevant in vitro models of epithelial tissues and engineered cell models that mimic disease in order to understand normal tissue homeostasis and human pathology.