As Professor of Clinical Science, I have experience in leading a broad programme of research in human trauma and surgery.  Working in universities in the UK and overseas, my focus is translational research. In recognition of my scientific work, I have received six international awards in the field of burns, brain trauma, surgery and wound infection.  

I currently lead the Applied Imaging research theme for the Centre for Applied Health and Social Care Research.

After qualifying, care of burned children inspired my research interests. I received National/International recognition winning a number of scientific prizes in paediatric trauma. Later, as an MRC scientist, I led the metabolic research programme on childhood burns. Building a bespoke calorimeter to measure energy expenditure, our ‘metabolic-cart’ became the prototype for later commercial systems. 

By 2000, injured brain became my research focus. Pioneering new, implantable, brain sensors, the objective was to forge new ways to reduce secondary, ischaemic brain damage. Results were controversial, challenging existing dogma, specifically on brain temperature. 

In 2009, invited to the National University of Singapore, I explored new invasive and non-invasive imaging modalities for sepsis, brain-injury diagnosis and wound infection. Back in the UK, my research programme combines my interests of non-invasive imaging diagnosis in trauma; the injured body (with a focus on surgical site infection) and, as we enter an era of brain injury awareness, the injured brain; specifically concussion in sport. Most recently my research path has reached another fork in my scientific journey, applying my imaging skills in the field of endovascular revascularisation.  

Within Health and Social Care Research, I lead the Applied Imaging theme.

Research Interests:

• TRAUMA and SURGERY
• Vascular assessment and thermal perfusion imaging
• Surgical site infection 
• Severe traumatic brain injury and neurocritical care
• Concussion in sports
• Human thermoregulation: fever and brain cooling
• Sepsis

IMAGING
Invasive multiparameter neuromonitoring (temperature, pressure and oxygen content), 1HMR spectroscopy, long wave dynamic infrared  thermography, Optical Coherence Tomography (OCT), Automated Pupillometry. 
 

Research Interests: TRAUMA and SURGERY

• Peripheral vascular disease and Critical linb-threatening ischaemia
• Surgical site infection and wound healing
• Severe traumatic brain injury and neurocritical care
• Concussion in sports
• Human thermoregulation: fever and brain cooling
• Prognostic performance of serum biomarkers
• Sepsis

IMAGING
Advanced, invasive multiparameter neuromonitoring (temperature, pressure and oxygen content)

Non-invasive Imaging

• Magnetic resonance spectroscopy (1HMRS) and imaging (1HMRSI)
• Non-invasive infra-red thermal imaging
• Optical coherence tomography (OCT) and retinal imaging.